Micelle-templated, poly(lactic-<em>co</em>-glycolic acid) nanoparticles for hydrophobic drug delivery

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منابع مشابه

Micelle-templated, poly(lactic-co-glycolic acid) nanoparticles for hydrophobic drug delivery

Purpose Poly(lactic-co-glycolic acid) (PLGA) is widely used for drug delivery because of its biocompatibility, ability to solubilize a wide variety of drugs, and tunable degradation. However, achieving sub-100 nm nanoparticles (NPs), as might be desired for delivery via the enhanced permeability and retention effect, is extremely difficult via typical top-down emulsion approaches. Methods Her...

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BACKGROUND Nanoparticles fabricated from the biodegradable and biocompatible polymer, polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug delivery systems. The objective of this study was to explore fully the development of a PLGA nanoparticle drug delivery system for alternative preparation of a commercial formulation. In our nanoparticle fabrication, ou...

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ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2018

ISSN: 1178-2013

DOI: 10.2147/ijn.s142079